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Results for "

collagen adhesion

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

4

Peptides

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107588
    TC-I 15

    		Integrin Cardiovascular Disease
    TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition .
    TC-I 15
  • HY-P1408A
    Obtustatin triacetate

    		Integrin Cancer
    Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .
    Obtustatin triacetate
  • HY-P1408
    Obtustatin

    		Integrin Cancer
    Obtustatin is a non-RGD disintegrin of 41 residues. Obtustatin can be isolated from Vipera lebetina obtusa venom. Obtustatin is a potent and selective inhibitor of the adhesion of integrin α1β1 to collagen IV. Obtustatin inhibits angiogenesis, and can be used for research of cancer .
    Obtustatin
  • HY-N7316
    Frangulin B

    		Others Inflammation/Immunology
    Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion .
    Frangulin B
  • HY-N4228
    6-Methoxydihydroavicine

    		Platelet-activating Factor Receptor (PAFR) Cancer
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro .
    6-Methoxydihydroavicine
  • HY-113612A
    Cytostatin sodium

    		Apoptosis Phosphatase Cancer
    Cytostatin sodium is an effective and selective protein phosphatase 2A (PP2A) inhibitor with an IC50 value of 210 nM. Cytostatin sodium exhibits anti-metastatic properties, good antitumor activity, and can induce apoptosis. Cytostatin sodium can also prevent the adhesion of B16 melanoma cells to components of the extracellular matrix (laminin and collagen). Cytostatin sodium belongs to the family of natural product fosriecin .
    Cytostatin sodium
  • HY-P1181
    Pam2CSK4

    		Toll-like Receptor (TLR) Inflammation/Immunology
    Pam2CSK4, a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 also activates iNOS expression and NO production in mouse macrophages .
    Pam2CSK4
  • HY-P1181A
    Pam2CSK4 TFA

    		Toll-like Receptor (TLR) Inflammation/Immunology
    Pam2CSK4 (TFA), a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 (TFA) promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 (TFA) also activates iNOS expression and NO production in mouse macrophages .
    Pam2CSK4 TFA

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